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OLIGO引物設計和分析軟體 Molecular Biology Insights Oligo 7.57

OLIGO引物設計和分析軟體 Molecular Biology Insights Oligo 7.57

OLIGO引物分析軟體的設計和分析測序和PCR引物,合成的基因,和各種種內含siRNA和分子信標探針是必不可少的工具。
基於最先進的迄今為止最近的鄰居的熱力學資料,寡核甘酸的搜尋算法找到最佳的引物進行PCR,TaqMan探針,高度復用,形成共識或簡並引物。
多個檔案的批處理是可能的。為定點突變,這也是一個非常寶貴的工具。
對於每一個引物或引物對,寡核甘酸的各種分析視窗示出了大量的有用的資料,如DNA和RNA的二級結構,二聚體的形成,虛假吸和同源性,內定的穩定性,組合物和物理性質。
用Oligo可以分析的開放閱讀框預測分子量和pKa的蛋白質,和限制性內切酶位點的搜尋,不僅在DNA而且在反向翻譯的蛋白質的。

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OLIGO引物設計和分析軟體 Molecular Biology Insights Oligo 7.57特點:
該軟體的第一個版本於1989年出現在市場上。
它經歷了若干修改,最後一個,6~7版本的變化,是最全面的。
寡7可以自動選取多重引物,在批處理模式過程式列檔案,自動設計PCR引物,覆蓋多個DNA區功能變數在短短的一個搜尋,並自動實時PCR的引物/探針套或發現引物集。
(評分系統)寡搜尋協定,可自訂的細節,所以你可以改善的結果,根據您的特定需求。
寡糖在Macintosh和Windows上運行,它可以從這個網站下載。
教學點擊上面的連結看到寡核甘酸的一般概況和主要的Windows螢幕設計。

OLIGO Primer Analysis Software is the essential tool for designing and analyzing sequencing and PCR primers, synthetic genes, and various kinds of probes including siRNA and molecular beacons.
Based on the most up-to date nearest neighbor thermodynamic data, Oligo's search algorithms find optimal primers for PCR, including TaqMan, highly multiplexed, consensus or degenerate primers. Multiple file batch processing is possible. It is also an invaluable tool for site directed mutagenesis.
For each primer or primer pair, Oligo's various analysis windows show a multitude of useful data, such as DNA and RNA secondary structure, dimer formation, false priming and homology, internal stability, composition and physical properties. With Oligo you can analyze open reading frames down to predicted molecular weight and pKa of proteins, and search for restriction enzyme sites, not only in DNA but also in reverse-translated proteins.


The first version of the software appeared on the market in 1989. It went through several modifications, and the last one, the change from version 6 to 7, was the most comprehensive. Oligo 7 can automatically select multiplex primers, process sequence files in batch modes, automatically design PCR primers to cover multiple DNA regions in just one search and automatically find primer/probe sets for real time PCR or finds nested primers sets. Oligo search protocols (scoring system) may be customized in detail, so you may optimize the results according to your specific needs.
Oligo runs on Macintosh and Windows and it may be downloaded from this site. Click on the Tutorials link above to see Oligo 7 general overview and the major windows screen designs.

OLIGO引物設計和分析軟體 Molecular Biology Insights Oligo 7.57 | Home Page www.oligo.net


OLIGO引物設計和分析軟體 Molecular Biology Insights Oligo 7.57 / Size: 13.1 MB


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